The narrowing olfactory landscape of insect odorant receptors

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The narrowing olfactory landscape of insect odorant receptors

The molecular basis of odorant detection and its corollary, the task of the odorant receptor, are fundamental to understanding olfactory coding and sensory ecology. Based on their molecular receptive range, olfactory receptors have been classified as pheromone and non-pheromone receptors, which are respectively activated by a single pheromone component (“specialist”) or by multiple odorant liga...

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Tuning Insect Odorant Receptors

Citation: Wicher D (2018) Tuning Insect Odorant Receptors. Front. Cell. Neurosci. 12:94. doi: 10.3389/fncel.2018.00094 Among the insect olfactory receptors the odorant receptors (ORs) evolved in parallel to the onset of insect flight. A special property of this receptor type is the capability to adjust sensitivity of odor detection according to previous odor contacts. This article presents a cu...

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Insect Odorant Receptors: Channeling Scent

Odorant detection in insects involves heterodimers between an odorant receptor (OR) and a conserved seven-transmembrane protein called Or83b, but the exact mechanism of OR signal transduction is unclear. Two recent studies in Nature (Sato et al., 2008; Wicher et al., 2008) now reveal that these OR-Or83b heterodimers form odorant-gated ion channels, revealing a surprising new mode of olfactory t...

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Evolution of insect olfactory receptors

The olfactory sense detects a plethora of behaviorally relevant odor molecules; gene families involved in olfaction exhibit high diversity in different animal phyla. Insects detect volatile molecules using olfactory (OR) or ionotropic receptors (IR) and in some cases gustatory receptors (GRs). While IRs are expressed in olfactory organs across Protostomia, ORs have been hypothesized to be an ad...

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Insects possess one of the most exquisitely sensitive olfactory systems in the animal kingdom, consisting of three different types of chemosensory receptors: ionotropic glutamate-like receptors (IRs), gustatory receptors (GRs) and odorant receptors (ORs). Both insect ORs and IRs are ligand-gated ion channels, but ORs possess a unique configuration composed of an odorant-specific protein OrX and...

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ژورنال

عنوان ژورنال: Frontiers in Ecology and Evolution

سال: 2015

ISSN: 2296-701X

DOI: 10.3389/fevo.2015.00039